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Premier League, Manchester City vs Chelsea： Triple Crown and Triple Crown

Manchester City, the third consecutive champion, played against Chelsea at home this Sunday, ending the home game this season.

Regardless of the outcome, Manchester City will receive the Premier League trophy after the game. Chelsea seek revenge, and Manchester City have lost all three games this season, including a 1-0 defeat at Stamford Bridge in January, and riyad mahrez scored in the second half.

Twenty-four years ago, Manchester City could only watch its arch-rival Manchester United win the triple crown. Now history is in front of Manchester City, and Manchester City is expected to win three awards this season and write a page of football legend.

Guardiola’s success team advanced to the Champions League final, beating defending champion Real Madrid 4-0 at home on Wednesday. Silva scored twice, and Acani and Alvarez also scored. On June 10th, they played against Inter Milan in Istanbul.

A week ago, the FA Cup Manchester Derby final was put on the agenda. Now that a trophy has been brought home, with Nottingham Forest beating Arsenal 1-0 at home, Guardiola is guaranteed to lead the team to three consecutive championships-only Manchester United achieved it from 1998 to 2001 and from 2006 to 2009.

Manchester City is 4 points ahead of Arsenal, the second place, and the peak is unparalleled. They enjoyed a winning streak as expected, winning the last 11 rounds of the league. The results of home games are amazing, with 16 wins since the new year and only 7 goals lost after 56 goals.

The winning streak at home began with an easy 4-0 victory over Chelsea in the third round of FA Cup in January. Since losing to Chelsea in the Champions League final in Porto, Portugal in 2021, Manchester City has won five games without conceding a goal.

Champagne has cooled down, Guardiola and others hope that the final game at home this season will end with a victory over Chelsea, and then lift the Premier League trophy with cheers at home.

Chelsea, which is 42 points behind Manchester City, seems to be in the lower half of the Premier League for the first time since the 1995-1996 season. Last weekend, the forest threatened by relegation drew 2-2.

Rem Sterling scored twice in the seventh minute of the second half, but Nigerian striker taiwo Awoniyi equalized in the 60th minute to help the visiting team win a point at Stamford Bridge.

Lampard ranks 11th in the scoresheet, eight points behind 10th, the arch-rival Fulham across the Thames, and the chances of winning the remaining three games against Manchester City, Manchester United and Newcastle are slim.

Chelsea haven’t won 14 consecutive Premier League games against the team above the standings, and Manchester City has lost 6 games and won 1 game in the last 7 games.

summary

I expect Manchester City to score 3-0 against Chelsea.

Even if Guardiola rotates the lineup, Manchester City is strong enough to beat Chelsea, which is only fighting for honor and ending the season in the experimental stage.

Manchester City won the last home league game eight times in the last nine seasons. We expect them to do the same tonight and end their unforgettable season in a perfect way.

Cheer, Manchester City fans! Three consecutive championships, three championships in sight, Manchester City has become a legend of English football! No matter what the result is, under the leadership of coach Guardiola, we all enjoy such a brilliant moment. Let’s shout Manchester City!

Chelsea fans, don’t lose heart. Our blue army is in the reconstruction period, and it is difficult to make much progress in the short term, but the team is full of top Premier League stars and its strength is still there. At the beginning of the new season, we are sure to regain our former glory and make great achievements on the Premier League stage again. Chelsea! Chelsea!

Masters, no matter which side you are on, this BIG6 war is not to be missed.

So, which team do you like? Manchester City’s dream of winning three consecutive championships and treble, or Chelsea’s reconstruction breakthrough?

If you have any questions, please feel free to ask them in the comments section. Your question will be an opportunity for me to improve, and I will definitely answer it seriously. Please rest assured. Finally, I hope we can share the fun of this game together and look forward to your active discussion!

Guizhou University of Finance and Economics Business College 2023 Spring Track and Field Games

On the morning of April 20th, the 2023 Spring Sports Meeting of Business College of Guizhou University of Finance and Economics and Qiannan Economic College of Guizhou Province, with the theme of "Exercise strengthens physique and youth shows style", kicked off in the college football field.

Zhou You, Dean of Business College of Guizhou University of Finance and Economics and Qiannan Economic College of Guizhou, announced the opening of the Games, and Shu Yu, Vice President, delivered the opening speech. The opening ceremony was presided over by Zhang Lujun, Vice President. College leaders, heads of secondary colleges (departments) and departments, and nearly 20,000 teachers and students from the whole school attended the opening ceremony.

With the passionate national anthem, the opening ceremony officially began. Wu Xukun, a faculty member, and Shi Shiwei, a student, took the oath on behalf of referees and athletes respectively. At the opening ceremony, the teams of all colleges strode forward and showed their heroic spirit. A total of 12 teams participated in the parade and display in this sports meeting. Their firm eyes are their unyielding quality, and their confident pace is their flying youth.

The sports meeting schedule is divided into two groups: the student group and the faculty group, with a total of 12 events. Teachers and students from 6 colleges participated in the sports meeting. On the afternoon of April 21st, all the sports events of the Games ended, and the closing ceremony and awarding ceremony of the Games were held in the college football field. After two days of fierce competition, the athletes have achieved excellent results.

In the end, the Accounting College, the Law College and the Finance College won the first, second and third place in the group with 174 points, 95 points and 88 points.

The success of this spring sports meeting not only showed the passion and vitality of the teachers and students of the Academy, but also carried forward the spirit of hard work and unity. I hope that in the future development, we can always maintain such a mental outlook and add the most beautiful life background to our lives.

Photo source: News Center of Qiannan Economic College, Guizhou

Editor: Yang Zhiyu Liu Guoyong Pi Wang Yanping Wang Ganmei

Zhu Guang, CEO of Du Xiaoman： Actively deploy the application of large model technology in the financial field

On March 9 th, Zhu Guang, CEO of Du Xiaoman, said in a signed article that Du Xiaoman has been actively deployed in exploring the application of large model technology in the financial industry.

Large models can be divided into comprehensible large models and generative large models. In Zhu Guang’s view, the comprehensible big model raises the decision-making ability of customer management and risk control to a new height and reduces financial risks; Generative AI will focus on customers, reshape the customer service process and experience, and become an "always-on super financial consultant" and an "all-round business assistant". This means that big model technology is defining a new entrance to the industry.

It is reported that Du Xiaoman has developed a series of applications based on large models relying on Baidu artificial intelligence technology. Taking risk management as an example, Du Xiaoman has applied LLM, a large language model, to the interpretation of Internet text data and credit report. Through the pre-training model constructed with text data and AI algorithm, he can interpret the credit report into 400,000-dimensional risk variables and better identify the credit risk of small and micro business owners. With the iteration of the model, the potential of the large model in intelligent risk control will be further released.

The self-developed voice robot can realize multiple rounds of complex conversations, with a non-inductive rate of 99%, that is, 99% of users don’t know that it is actually a robot talking to themselves, which can replace more than 60% repetitive work in credit business, and is widely used in marketing and collection work of many financial institutions, which greatly reduces labor costs and also has certain emotional recognition ability.

ChatGPT’s semantic understanding ability is also the key investment direction of Du Xiaoman in the field of natural language processing (NLP). In 2021, in the document sorting task of MS MARCO competition held by Microsoft, the NLP team ranked first and set a new record; The XuanYuan pre-training model developed by the team also ranks first in the CLUE classification task.

Baidu’s generative dialogue product "Wen Xin Yi Yan" (English name: ERNIE Bot) based on Wen Xin big model technology opened up ecological cooperation, and Du Xiaoman became the first financial technology company to access it. Next, based on the large-scale model technology base of Wenxin, combined with the financial industry knowledge and data accumulated in Xiaoman’s business scenario, Xiaoman will create a brand-new intelligent customer service, intelligent risk control and intelligent interactive service.

Zhu Guang said that the big model technology like GPT is the core topic of the next generation AI technology contest, which will have a profound impact on the intelligence level and digitization level of the financial industry. Financial technology companies should seize the opportunity window of this technological change, actively explore the application and development of large-scale model technology, and help the financial industry realize the leap from digitalization to intelligence.

Nature writes： In the next 30 years, cancer will cost the world 25 trillion US dollars.

Monoclonal antibody against B-cell psoriasis leukemia, a target of cancer artificial intelligence

①Nature：Cancer will cost the world $25 trillion over next 30 years

In the next 30 years, cancer may cost the world $25 trillion.

DOI :10.1038/d41586-023-00634-9

②Seminars in Cancer Biology：Artificial intelligence in cancer immunotherapy: applications in neoantigen recognition, antibody design and immunotherapy response prediction

Review: Application and development of artificial intelligence in the field of precision oncology: new antigen recognition, antibody design and immunotherapy response prediction.

DOI :10.1016/j.semcancer.2023.02.007

③Molecular Cancer：CD39/CD73/A2AR pathway and cancer immunotherapy

Review: New progress in pathophysiological function of CD39/CD73/A2AR pathway in cancer development, metastasis and drug resistance.

DOI :10.1186/s12943-023-01733-x

④Immunity：B cell receptor signaling in germinal centers prolongs survival and primes B cells for selection

B cell receptor signal transduction in germinal center prolongs the survival of B cells and initiates the selection of B cells.

DOI :10.1016/j.immuni.2023.02.003

⑤Frontiers in Immunology：Metabolic rewiring in keratinocytes by miR-31-5p identifies therapeutic intervention for psoriasis

The metabolic recombination of miR-31-5p in keratinocytes determines the intervention on psoriasis.

DOI :10.15252/emmm.202215674

⑥Journal of Hematology & Oncology：Novel agents and regimens in acute myeloid leukemia: latest updates from 2022 ASH Annual Meeting

The latest drug research and new scheme progress of American Society of Hematology (ASH) for acute myeloid leukemia (AML)
DOI :10.1186/s13045-023-01411-x

⑦FDA extended the review of adult Roctavian with severe hemophilia A because of "significant changes in a large number of additional data"

⑧ A small molecule MET inhibitor, gumetinib, which was developed by Shanghai Institute of Pharmacology, China Academy of Sciences, was approved for marketing, and it was used for locally advanced or metastatic non-small cell lung cancer (NSCLC) with the jump mutation (METex14 jump) in exon 14 of mesenchymal-epithelial transforming factor (MET).

⑨ The clinical study of Relma-cel targeting CD19 for first-line high-risk large B-cell lymphoma was officially launched.

⑩ Lilly will terminate the research and development of Solanezumab for Alzheimer’s disease because it fails to slow down the cognitive decline of preclinical Alzheimer’s patients.

The world of scientific exploration is full of challenges. AtaGenix pays tribute to every pioneer and is more committed to becoming your trusted partner!